My Road Map - Advice appreciated.

Knaaks

First, my roster: https://mpq.gamependium.com/rosters/knaaks/

I made the very suspect decision to champ Devil Dino last night, but no regrets. YOLO, right? It involved cashing in 164 Savory Taco Tokens though, but I am not complaining because I got a lot of covers/HP/Health Packs from cashing them in. I already had all the 3 heroes in the vault champed already, so lots of levels for them too. Kind of mad I didn't get either of the 4 or the Legendary token though, but oh well. Anyway, it is now time for me to get serious and make a plan, so here is my road map over the next few months. Let me know if anything looks completely out of whack that I should change.

Priority A1 - Have enough ISO to champ Hulkbuster once I get his 14th cover. Iron Fist is sitting at 181, at 183 he will give me the last black cover I need for him to get to 13/13, then IM40 is at 178. By the time IM40 is 183, I need to have about 200K ISO to champ him.

Priority A2 - Level up 4 heroes so I can beat their Crash of the Titans. Taking a look at the upcoming crashes, I should be able to beat Sam Wilson and Cyclops if I put ISO in to them. After that, the next one I think I will need to spend ISO on is Thor Godess of Thunder, that isn't for a while, so I should be ok.

Priority B1 - Level up the rest of my 3 heroes. I have 6 left, in order of how relevant their 4 reward is, the order I am going to do them is: Sentry, Ragnarok, Loki, Dr. Ock, Gamora, Dr. Doom. I realize that Gamora and Dr. Doom are probably the "best" out of that group of six, but I already have Invisible Woman at 13/13, and have no plans to champ her any time soon. Gamora, I could use the Star Lord cover, and she might move up on this list if SL gets a buff.

Priority B2 - Keep cycling through my 2 heroes. I just sold maxed Storm and Torch, I plan on getting them back champed ASAP because they are handy for Deadpool Daily. I want to do Moonstone because Hulk covers will be helpful. I am not in a rush for Ares or Bullseye, because I don't have Ragnarok champed yet, and 3 Bullseye gives me a Kingpin cover that I already have 5 of, but he is not close to 5 on his other covers. If it comes down to it, I will prioritize the ISO spending in level of rarity, so 4 > 3 > 2.

Once all of this is done, I am going to start saving up ISO again, and then start opening Legendary tokens again. I have 11 Latest Legendary, and 135 CP saved up now, but honestly I will probably not be able to resist opening my Latests if Dr. Strange is a 5 star. Then I am going to start saving up and champing 4's as I get enough covers for them.

madok

Sounds like a great plan. Biggest thing is working on getting that ISO reserve built up so when you dip into it you aren't completely depleting it. Until the anniversary hit, I've been trying to keep at least 250,000 ISO banked so I could be flexible in what I was doing. It makes the game a whole lot stressful when you aren't trying to beat the clock on expiring covers in your queue.

Zyrook

You've got a good road-map planned out, though I'd consider champing HB as soon as you get that 13th rather than wait for the 14th, if only to respect him. For the longest time I had HB at 5/2/5 due to poor draws. Believe me that 5 black makes a world of difference.

The level needed for Clash of the Titans varies radically from character to character, though I tend to have a lot of luck around the 130 range. My advice is to give it a few tries as is, then pump 5-10 levels in and try again. That way you're not dumping too much ISO in places you don't need to. Though leveling 4Cyke is never a bad idea.

Of the 3*s I'd consider Rags and Sentry to be honest. Doc Oc is kinda fun PVE and Patches' green is a good set up for his blue. Gamora is the most playable of the lot. But Rags and Sentry give the best covers, with X-23 and Rulk respectively. Rulk isn't all that fun to play, but he's crazy effective, especially when boosted.

Calnexin

You've got a good roadmap here, but I'd switch priorities.

1 - 2* cycling. Except for Bullseye. You're not ready for the Kingpin cover, so let it slide until you are. Otherwise, the 2* cycling is lucrative. Technically Iso-negative, but only if you place no value on XP, CP, HP, and tokens.

2 - Crash candidates. If you earn a cover you can't use, you have 2 weeks to earn the Iso to make it useful. The opportunity for that LT disappears in 24 hr. Any viable candidate should be brought up to a level where you can earn that token.

3 - HB. No ring rust on him - he's still relevant. But it's a big investment. As much as you want to champ him right away, think about your personal economy first. You might bankrupt yourself doing it and then be wanting for resources when something enticing drops in your lap.

4 - 3*. They're not going anywhere, and since you have all of them you can earn all of the DDQ rewards. Selling a couple covers bears less opportunity cost than a non-champed Hulkbuster or loss of an LT.